Vitamin B12 is an extremely important vitamin naturally found in meat and dairy products. Our body uses vitamin B12 to support our brain and nervous system.

Vitamin B12 is also used to treat fatigue, increase immunity to disease, and encourage natural sleep patterns, alongside other amazing benefits.

In this post, we cover the most popular vitamin B12 supplements and help you decide which supplement is the best for your body and lifestyle.

Best Vitamin B12 Supplement

Understanding Vitamin B12

Vitamin B12 is used by our body to support the functions of our brain and nervous system. B12 is found naturally in many meat, fish, and dairy products. For people who are vegetarian or vegan, vitamin B12 deficiencies can be common.

Maintaining regular B12 levels is crucial for a healthy lifestyle. If untreated, a significant vitamin B12 deficiency can prove to be detrimental to your nervous system and brain. Vitamin B12 is a popular supplement, especially among people who are vegetarian or vegan. The most popular forms of vitamin B12 that are used as a supplement are cyanocobalamin and methylcobalamin.

Aside from the vital health impacts that vitamin B12 has on our body, there are some amazing benefits that come with the correct vitamin B12 levels. By keeping your vitamin B12 levels stable, you can expect to sleep better, lose weight, boost energy, and have a more positive outlook on life.


Cyanocobalamin is the most common form of vitamin B12 on the market, referred to as just vitamin B12. Chemically, cyanocobalamin is the most stable form of vitamin B12, which contributes to its safety and effectiveness. Cyanocobalamin is converted to methylcobalamin in the body.


Methylcobalamin, typically referred to as methyl B12, is the active form of vitamin B12. However, it’s considered a less popular form of vitamin B12 available on the market. This form of vitamin B12 is considered to be chemically less stable than the cyanocobalamin form of vitamin B12. Therefore, most people prefer to use cyanocobalamin, rather than methylcobalamin as their preferred vitamin B12 supplement.

Delivery Methods

Vitamin B12 is best administered through intramuscular or subcutaneous injection, or an orally chewed tablet. An important factor in the efficacy of vitamin B12 is how well it is absorbed, which is directly connected to the delivery method of the supplement.

When taking vitamin B12, it’s important to consider other medications and supplements that you may be taking with your vitamin B12. Vitamin B12 may be absorbed less when paired with certain medications, which is why it is sometimes preferred to administer the vitamin via an injection to ensure the best absorption possible.

Bottom Line

Vitamin B12 deficiency can be dangerous if left untreated. People who are vegetarian or vegan need to pay special attention to their vitamin B12 levels, as we naturally receive vitamin B12 through meat, fish, and dairy products.

Vitamin B12 comes in two main forms, cyanocobalamin and methylcobalamin, which are both types of vitamin B12. Cyanocobalamin is the more stable, popular form of vitamin B12.

The method you choose to administer your dose of vitamin B12 is vital to the efficacy of the vitamin itself. At Medical Weight Loss Centers of America, we recommend injecting vitamin B12 on a regular schedule, to ensure your level of vitamin B12 stays consistent.

Which type of Vitamin B12 will you be trying?